CFG920
Product Specifications
CAS Number
1260006-20-9
Target
Others, Cytochromes P450
Related Pathways
Others, Metabolism
Bioactivity
CFG920 is a CYP17 inhibitor, is also an orally available inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential antiandrogen and antineoplastic activities. Upon oral administration, CYP17 inhibitor CFG920 inhibits the enzymatic activity of CYP17A1 in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells.
Smiles
O=C1N(CCN1C=2C=C(Cl)N=CC2)C=3C(C)=CC=NC3
Molecular Formula
C14H13ClN4O
Molecular Weight
288.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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