PF-00956980

Product Specifications

CAS Number

1262832-74-5

Target

Others|||JAK

Related Pathways

Stem Cells|||Others|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis

Bioactivity

PF-00956980 is a reversible pan-JAK inhibitor with IC50 values of 2.2 ?M for JAK1, 23.1 ?M for JAK2, and 59.9 ?M for JAK3, used in the study of lung and skin inflammatory diseases.

Smiles

N(C)(C1=C2C(NC=C2)=NC=N1)[C@H]3CN(C(=O)N4CCCC4)CC[C@H]3C

Molecular Formula

C18H26N6O

Molecular Weight

342.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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