PF-00956980
Product Specifications
CAS Number
1262832-74-5
Target
Others|||JAK
Related Pathways
Stem Cells|||Others|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis
Bioactivity
PF-00956980 is a reversible pan-JAK inhibitor with IC50 values of 2.2 ?M for JAK1, 23.1 ?M for JAK2, and 59.9 ?M for JAK3, used in the study of lung and skin inflammatory diseases.
Smiles
N(C)(C1=C2C(NC=C2)=NC=N1)[C@H]3CN(C(=O)N4CCCC4)CC[C@H]3C
Molecular Formula
C18H26N6O
Molecular Weight
342.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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