GSK1842799 HCl
Product Specifications
CAS Number
1277165-15-7
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000x selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK/PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical.
Smiles
Cl.Cl.CCCCCCCCOc1ccc(cc1C(F)(F)F)-c1nnc(s1)[C@@](C)(N)CO
Molecular Formula
C20H30Cl2F3N3O2S
Molecular Weight
504.4342
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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