MC2050 HCl
Product Specifications
CAS Number
1301757-19-6
Target
Others
Related Pathways
Others
Bioactivity
MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.
Smiles
Cl.Cl.O=c1nc(SCCN2CCN(CC2)c2ccccn2)[nH]c2ccccc12
Molecular Formula
C19H23Cl2N5OS
Molecular Weight
440.387
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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