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MC2050 HCl

Product Specifications

CAS Number

1301757-19-6

Target

Others

Related Pathways

Others

Bioactivity

MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 ?M for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.

Smiles

Cl.Cl.O=c1nc(SCCN2CCN(CC2)c2ccccn2)[nH]c2ccccc12

Molecular Formula

C19H23Cl2N5OS

Molecular Weight

440.387

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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