What is the catalog number for AT-1001?

The catalog number for AT-1001 is T70987.

What sizes are available for AT-1001?

AT-1001 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does AT-1001 come in?

AT-1001 is available in 3 different pack sizes.

AT-1001 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AT-1001?

AT-1001 is manufactured by Molfinity.

What is the estimated delivery time for AT-1001?

Estimated delivery time for AT-1001 is approximately 10 business day(s), depending on your location.

AT-1001

Product Specifications

CAS Number

1314801-63-2

Target

AChR, Others

Related Pathways

Neuroscience, Others

Bioactivity

AT-1001 is an α3β4 nAChR partial agonist. AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats. AT-1001 also potently and reversibly blocks epibatidine-induced inward currents in HEK cells transfected with α3β4 nAChR. Importantly, AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding. When tested in a nucleus accumbens (NAcs) synaptosomal preparation, AT-1001 inhibits nicotine-induced [3H]dopamine release poorly and at significantly higher concentrations compared with mecamylamine and conotoxin MII.