EST64454 free base
Product Specifications
CAS Number
1351438-26-0
Target
Others|||Sigma receptor
Related Pathways
GPCR/G Protein|||Others
Bioactivity
EST64454 is a ?1 receptor (?1R) antagonist clinical candidate for the treatment of pain. EST64454 shows an outstanding aqueous solubility, which together with its high permeability in Caco-2 cells will allow its classification as a BCS class I compound. It also shows high metabolic stability.
Smiles
C(OCCN1CCN(C(C)=O)CC1)C2=NN(C=C2)C3=CC(F)=C(F)C=C3
Molecular Formula
C18H22F2N4O2
Molecular Weight
364.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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