K811
Product Specifications
CAS Number
1355228-38-4
Target
Others
Related Pathways
Others
Bioactivity
K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.
Smiles
C(C)(C)N1C=2C(C(=O)C(C(NC3=CC=C(OC=4C5=C(C=C(OC)C(OC)=C5)N=NC4)C=C3)=O)=C1)=CC=CC2
Molecular Formula
C29H26N4O5
Molecular Weight
510.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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