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ML309

Product Specifications

CAS Number

1355446-05-7

Target

Others

Related Pathways

Others

Bioactivity

ML309 is a potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells. ML309 is capable of potent and selective inhibition of mutant IDH1 and effectively lowers cell-based production of 2-HG in a U87MG mutant glioblastoma cell line.

Smiles

C(N(C(CN1C=2C(N=C1)=CC=CC2)=O)C3=CC(F)=CC=C3)(C(NC4CCCC4)=O)C5=C(C)C=CC=C5

Molecular Formula

C29H29FN4O2

Molecular Weight

484.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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