ML309
Product Specifications
CAS Number
1355446-05-7
Target
Others
Related Pathways
Others
Bioactivity
ML309 is a potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells. ML309 is capable of potent and selective inhibition of mutant IDH1 and effectively lowers cell-based production of 2-HG in a U87MG mutant glioblastoma cell line.
Smiles
C(N(C(CN1C=2C(N=C1)=CC=CC2)=O)C3=CC(F)=CC=C3)(C(NC4CCCC4)=O)C5=C(C)C=CC=C5
Molecular Formula
C29H29FN4O2
Molecular Weight
484.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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