PT-S58
Product Specifications
CAS Number
1356497-92-1
Target
Others|||PPAR
Related Pathways
Metabolism|||Others|||DNA Damage/DNA Repair
Bioactivity
PT-S58 is a PPAR ?/? full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPAR?/?. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.
Smiles
S(NC1=C(OC)C=C(NC(C)(C)C)C=C1)(=O)(=O)C2=C(C(OC)=O)SC=C2
Molecular Formula
C17H22N2O5S2
Molecular Weight
398.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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