Ent-Abacavir
Product Specifications
CAS Number
136470-79-6
Target
Others
Related Pathways
Others
Bioactivity
Ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Smiles
N(C1=C2C(N(C=N2)[C@H]3C[C@@H](CO)C=C3)=NC(N)=N1)C4CC4
Molecular Formula
C14H18N6O
Molecular Weight
286.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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