BMS-351
Product Specifications
CAS Number
1370001-71-0
Target
Cytochromes P450|||Others
Related Pathways
Others|||Metabolism
Bioactivity
BMS-351 is a potent and selective, nonsteroidal CYP17A1 lyase inhibitor with robust selectivity over steroidogenic CYPs 21A2 and 11B1. BMS-351 emerges as an outstanding preclinical candidate to treat CRPC and is likely to minimize the side effects of current therapies due to its exceptional selectivity. BMS-351 is potentially useful for the Treatment of Prostate Cancer.
Smiles
C(C(F)(F)F)N1C=2C(=C(C=CC2)C=3C(C)=CC=NC3)N=C1
Molecular Formula
C15H12F3N3
Molecular Weight
291.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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