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CM-118

Product Specifications

CAS Number

1370652-56-4

Target

Others

Related Pathways

Others

Bioactivity

CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF) -induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells.

Smiles

O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C=2C=C(C(NC3=CN(C)C(=O)C=C3)=O)N=NC2N

Molecular Formula

C19H16Cl2FN5O3

Molecular Weight

452.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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