RO27-3225 TFA
Product Specifications
CAS Number
1373926-49-8
Target
TNF, Melanocortin Receptor, Interleukin, Others
Related Pathways
Apoptosis, Others, GPCR/G Protein, Immunology/Inflammation, Neuroscience
Bioactivity
RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.
Smiles
OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)CC(N)=O
Molecular Formula
C41H53F3N12O8
Molecular Weight
898.9462
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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