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CRV431

Product Specifications

CAS Number

1383420-08-3

Target

Others, Sirtuin, Interleukin

Related Pathways

Others, DNA Damage/DNA Repair, Immunology/Inflammation, Chromatin/Epigenetic

Bioactivity

CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM) .

Smiles

[C@H]([C@@H](CCCCCCNC(C)=O)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](CC)NC1=O)[H]

Molecular Formula

C67H122N12O13

Molecular Weight

1303.76

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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