CRV431
Product Specifications
CAS Number
1383420-08-3
Target
Others|||Sirtuin|||Interleukin
Related Pathways
Others|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Chromatin/Epigenetic
Bioactivity
CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM) .
Smiles
[C@H]([C@@H](CCCCCCNC(C)=O)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](CC)NC1=O)[H]
Molecular Formula
C67H122N12O13
Molecular Weight
1303.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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