Lanabecestat HCl
Product Specifications
CAS Number
1383986-31-9
Target
Others|||Beta-Secretase
Related Pathways
Neuroscience|||Others
Bioactivity
Lanabecestat, also known as AZD3293 and LY3314814, is a potent, highly permeable, orally active, blood-brain barrier (BBB) penetrating, BACE1 inhibitor with unique slow off-rate kinetics. AZD3293 displayed significant dose- and time-dependent reductions in plasma, cerebrospinal fluid, and brain concentrations of A?40, A?42, and sA?PP?.
Smiles
Cl.CO[C@H]1CC[C@@]2(Cc3ccc(cc3[C@@]22N=C(C)C(N)=N2)-c2cncc(c2)C#CC)CC1
Molecular Formula
C26H29ClN4O
Molecular Weight
448.995
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7227150-01 48 Well
Rat Glutamate receptor, ionotropic kainate 1 (GRIK1) ELISA Kit
Ask
View Details MBS7227150-02 96 Well
Rat Glutamate receptor, ionotropic kainate 1 (GRIK1) ELISA Kit
Ask
View Details MBS7227150-03 5x 96 Well
Rat Glutamate receptor, ionotropic kainate 1 (GRIK1) ELISA Kit
Ask
View Details 
MBS7227150-04 10x 96 Well
Rat Glutamate receptor, ionotropic kainate 1 (GRIK1) ELISA Kit
Ask
View Details ![Rabbit Monoclonal AdipoR1 Antibody (2416C) [mFluor Violet 610 SE]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
FAB10128MFV610 0.1 mL
Rabbit Monoclonal AdipoR1 Antibody (2416C) [mFluor Violet 610 SE]
Ask
View Details