Elenbecestat free base
Product Specifications
CAS Number
1388149-39-0
Target
Beta-Secretase|||Others
Related Pathways
Neuroscience|||Others
Bioactivity
Elenbecestat, also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of A? peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce A? levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.
Smiles
C(F)(F)(F)[C@@H]1[C@@]2([C@](CO1)(N=C(N)SC2)C3=CC(NC(=O)C=4C=NC(C(F)F)=CN4)=CC=C3F)[H]
Molecular Formula
C19H15F6N5O2S
Molecular Weight
491.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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