SPR519
Product Specifications
CAS Number
1391923-59-3
Target
Others
Related Pathways
Others
Bioactivity
SPR519 is a potent dual inhibitor of PI3Kα and mTOR kinases with IC50 (PI3Kalpha) = 30 nM and IC50 (mTOR) = 10 nM. SPR519 exhibits an EC50 of low sub-micromolar range among various tested cancer cell lines such as A2780 (0.23 μM), PC3 (0.48 μM), and SKOV3 (0.50 μM) .
Smiles
O(C=1N=C(N=C(N1)N2CCOCC2)C=3SC(N)=NC3)C4=CC=C(C(N(C)C)=O)C=C4
Molecular Formula
C19H21N7O3S
Molecular Weight
427.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
249826-FITC 100 µL
PCDH10 (Protocadherin 10, DKFZp761O2023, KIAA1400, MGC133344, OL-PCDH, PCDH19) (FITC)
Sign In for Pricing
View Details 
MBS9317638-01 48 Well
Dog Ras-related protein Rab-22A, RAB22A ELISA Kit
Sign In for Pricing
View Details MBS9317638-02 96 Well
Dog Ras-related protein Rab-22A, RAB22A ELISA Kit
Sign In for Pricing
View Details MBS9317638-03 5x 96 Well
Dog Ras-related protein Rab-22A, RAB22A ELISA Kit
Sign In for Pricing
View Details MBS9317638-04 10x 96 Well
Dog Ras-related protein Rab-22A, RAB22A ELISA Kit
Sign In for Pricing
View Details