NMS-P953
Product Specifications
CAS Number
1403679-33-3
Target
Others, JAK
Related Pathways
Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis, Others, JAK/STAT signaling, Chromatin/Epigenetic
Bioactivity
NMS-P953 is a JAK2 inhibitor, displaying significant tumor growth inhibition in SET-2 xenograft tumor model. NMS-P953 has a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile.
Smiles
C(N)(=O)C1=C(NC(=C1)C2=NC(N)=NC=C2)C3=CC(C(F)(F)F)=CC=C3Cl
Molecular Formula
C16H11ClF3N5O
Molecular Weight
381.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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