What is the catalog number for HJC-0123?

The catalog number for HJC-0123 is T70686.

What sizes are available for HJC-0123?

HJC-0123 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does HJC-0123 come in?

HJC-0123 is available in 3 different pack sizes.

Is HJC-0123 in stock?

HJC-0123 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HJC-0123?

HJC-0123 is manufactured by Molfinity.

What is the estimated delivery time for HJC-0123?

Estimated delivery time for HJC-0123 is approximately 10 business day(s), depending on your location.

HJC-0123

Product Specifications

CAS Number

1430420-02-2

Target

Apoptosis, STAT, Others, Interleukin, TGF-beta/Smad

Related Pathways

JAK/STAT signaling, Apoptosis, Immunology/Inflammation, Others, Stem Cells

Bioactivity

Downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values. Furthermore, HJC-0123 significantly suppressed estrogen receptor (ER) -negative breast cancer MDA-MB-231 xenograft tumor growth in vivo (p.o.), indicating its great potential as an efficacious and orally bioavailable drug candidate for human cancer therapy.