P38-α MAPK-IN-5
Product Specifications
CAS Number
1443242-46-3
Target
P38 MAPK, Others
Related Pathways
Others, MAPK
Bioactivity
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds potential for research in asthma and chronic obstructive pulmonary disease (COPD) .
Smiles
O(C1=CN2C(=NN=C2C=C1)N3[C@@H](C)CCCC3)[C@H]4C=5C([C@@H](NC(NC=6N(N=C(C(C)(C)C)C6)C7=CN(CCN(C)C)N=C7)=O)CC4)=CC=CC5
Molecular Formula
C37H49N11O2
Molecular Weight
679.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6423549-01 0.1 mL
JUN, Phosphorylated (T93) (Activator Protein 1, AP1, AP-1, c-Jun) (APC)
Sign In for Pricing
View Details MBS6423549-02 5x 0.1 mL
JUN, Phosphorylated (T93) (Activator Protein 1, AP1, AP-1, c-Jun) (APC)
Sign In for Pricing
View Details 