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ACT-672125

Product Specifications

Target

Others|||CXCR

Related Pathways

Autophagy|||Immunology/Inflammation|||GPCR/G Protein|||Others

Bioactivity

ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.

Smiles

C(F)(F)(F)C1=NC(=C(S1)N2C[C@@H](C)N(C(CN3C(C)=NC(C)=N3)=O)CC2)C=4NC=5C(N4)=CC=C(C5)C6=NOC(C)=N6

Molecular Formula

C25H25F3N10O2S

Molecular Weight

586.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/B19B7F09-CC74-49AB-9B0E-CE9F2BD432B4/T70616

CAS Number

1449367-94-5

Available Sizes

Curated Selection

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