Pibrozelesin
Product Specifications
CAS Number
154889-68-6
Target
Others, Antibiotic
Related Pathways
Microbiology/Virology, Others
Bioactivity
Pibrozelesin is a water-soluble derivative of duocarmycin B2 that alkylates DNA by binding to adenine-thymine (A-T) -rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.
Smiles
C(Br)[C@H]1C=2C3=C(C(OC(=O)N4CCN(C)CC4)=CC2N(C(=O)C=5NC=6C(C5)=CC(OC)=C(OC)C6OC)C1)NC(C)=C3C(OC)=O
Molecular Formula
C32H36BrN5O8
Molecular Weight
698.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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