HM5023507
Product Specifications
CAS Number
1549740-86-4
Target
Others
Related Pathways
Others
Bioactivity
HM5023507, an orally active dual inhibitor of δγ isoforms in immune signaling. HM5023507 inhibited PI3Kδ and PI3Kγ isoforms with greater than 100-fold selectivity against PI3Kα and PI3Kβ in recombinant enzymatic assays and in primary human immune cells with an exquisite selectivity against other targets.
Smiles
O=C1N(C(=NN2C1=C(Cl)C=C2)[C@@H]3N(CC3)C=4C(C(C)=O)=CN=C(N)N4)C5=CC=CC=C5
Molecular Formula
C21H18ClN7O2
Molecular Weight
435.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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