TX-1123
Product Specifications
CAS Number
157397-06-3
Target
Others, Src, PKA, PKC, EGFR, COX, CaMK
Related Pathways
Angiogenesis, Others, Neuroscience, Immunology/Inflammation, Chromatin/Epigenetic, Cytoskeletal Signaling, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for COX2 and 15.7 μM for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.
Smiles
C(C)(C)(C)C1=C(O)C(C(C)(C)C)=CC(C=C2C(=O)C=CC2=O)=C1
Molecular Formula
C20H24O3
Molecular Weight
312.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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