PNU-145156E
Product Specifications
CAS Number
159537-58-3
Target
VEGFR, FGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
PNU-145156E (formerly FCE 26644) is a noncytotoxic small molecule that exerts antitumor activity through reversible complex formation with growth and angiogenic factors, thereby inhibiting their ability to induce angiogenesis. PNU-145156E is utilized in research on tumor vascularization, angiogenesis regulation, and the development of anti-angiogenic therapeutic strategies.
Smiles
O=C(NC=1C=C(C(=O)NC=2C=C(C(=O)NC3=CC=C4C=C(C=C(C4=C3)S(=O)(=O)O)S(=O)(=O)O)N(C2)C)N(C1)C)NC=5C=C(C(=O)NC=6C=C(C(=O)NC7=CC=C8C=C(C=C(C8=C7)S(=O)(=O)O)S(=O)(=O)O)N(C6)C)N(C5)C
Molecular Formula
C45H40N10O17S4
Molecular Weight
1121.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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