What is the catalog number for BAY 61-3606 HCl?

The catalog number for BAY 61-3606 HCl is T70377.

What sizes are available for BAY 61-3606 HCl?

BAY 61-3606 HCl is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does BAY 61-3606 HCl come in?

BAY 61-3606 HCl is available in 4 different pack sizes.

Is BAY 61-3606 HCl in stock?

BAY 61-3606 HCl is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BAY 61-3606 HCl?

BAY 61-3606 HCl is manufactured by Molfinity.

What is the estimated delivery time for BAY 61-3606 HCl?

Estimated delivery time for BAY 61-3606 HCl is approximately 10 business day(s), depending on your location.

BAY 61-3606 HCl

Product Specifications

CAS Number

1615197-10-8

Target

Others, Apoptosis, Syk

Related Pathways

Angiogenesis, Apoptosis, Others, Tyrosine Kinase/Adaptors

Bioactivity

BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL) -mediated apoptosis by inhibiting Cdk9. This compound has been used in a pre-clinical model to explore the feasibility of targeting Syk in the treatment of retinoblastoma.