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Lu AF58786

Product Specifications

CAS Number

1632368-13-8

Target

Others

Related Pathways

Others

Bioactivity

Lu AF58786 is a novel potent and selective inhibitor of LRRK2, inhibiting LRRK2 WT, the overactive variant G2019S, and the resistant mutant A2016T56 at 12 nM, 19 nM and 93 nM, respectively.

Smiles

C(#N)C=1C2=C(C=C(NC=3C=CN(C)N3)N=C2NC1)C4=CC(C)=CC=C4

Molecular Formula

C19H16N6

Molecular Weight

328.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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