JJO-1
Product Specifications
CAS Number
16722-44-4
Target
Others|||AMPK
Related Pathways
PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Others
Bioactivity
JJO-1 is a bi-quinoline that allosterically activates all AMPK ??? isoforms in vitro except complexes containing the ?3 subunit. JJO-1 does not directly activate the autoinhibited ? subunit kinase domain and differs among other known direct activators of AMPK in that allosteric activation occurs only at low ATP concentrations, and is not influenced by either mutation of the ? subunit adenylate-nucleotide binding sites or deletion of the ? subunit carbohydrate-binding module.
Smiles
N(=CC1=NC2=C(C=C1)C=CC=C2)C3=CC4=C(N=C3)C=CC=C4
Molecular Formula
C19H13N3
Molecular Weight
283.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/A188BE2B-B2F4-49C1-B082-D442C8E9BB6B/T70296
Available Sizes
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