KB-R7785
Product Specifications
CAS Number
168158-16-5
Target
Others|||MMP
Related Pathways
Proteases/Proteasome|||Others
Bioactivity
KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect by ameliorating insulin sensitivity through the inhibition of TNF-alpha production.
Smiles
[C@@H](NC([C@@H]([C@@H](C(NO)=O)C)CC(C)C)=O)(C(NC)=O)C1=CC=CC=C1
Molecular Formula
C18H27N3O4
Molecular Weight
349.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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