Roridin E
Product Specifications
CAS Number
16891-85-3
Target
Antibiotic, Others, Antifungal
Related Pathways
Others, Microbiology/Virology
Bioactivity
Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 μM, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM) . It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = <0.01 μM) .
Smiles
CC(O)C1OCC\C(C)=C\C(=O)OCC23CCC(C)=CC2OC2CC(OC(=O)\C=C/C=C/1)C3(C)C21CO1
Molecular Formula
C29H38O8
Molecular Weight
514.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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