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Roridin E

Product Specifications

CAS Number

16891-85-3

Target

Antibiotic, Others, Antifungal

Related Pathways

Others, Microbiology/Virology

Bioactivity

Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 μM, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM) . It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = <0.01 μM) .

Smiles

CC(O)C1OCC\C(C)=C\C(=O)OCC23CCC(C)=CC2OC2CC(OC(=O)\C=C/C=C/1)C3(C)C21CO1

Molecular Formula

C29H38O8

Molecular Weight

514.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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