FT-1101 free base
Product Specifications
CAS Number
1776060-36-6
Target
Others
Related Pathways
Others
Bioactivity
FT-1101 is an orally bioavailable, potent and selective BET inhibitor. FT-1101 binds to the acetylated lysine recognition motifs in the bromodomain sites of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histones. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to the inhibition of tumor cell growth. BET proteins, comprised of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth.
Smiles
O(C1=C2C(N(C(=O)C3CC3)[C@@H](C)CC2)=CC=C1C4=CN(N=C4)C5CCNCC5)C6CCC6
Molecular Formula
C26H34N4O2
Molecular Weight
434.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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