DDR1-IN-1 dihydrochloride
Product Specifications
CAS Number
1780303-76-5
Target
Discoidin Domain Receptor (DDR) |||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Others
Bioactivity
DDR1-IN-1 dihydrochloride is a selective and potent inhibitor of the DDR1 receptor tyrosine kinase, exhibiting an IC50 of 105 nM, and it demonstrates fourfold reduced potency against DDR2, with an IC50 of 413 nM.
Smiles
Cl.Cl.O=C(NC1=CC=C(C(OC2=CC=C3NC(=O)CC3=C2)=C1)C)C4=CC=C(C(=C4)C(F)(F)F)CN5CCN(CC)CC5
Molecular Formula
C30H33Cl2F3N4O3
Molecular Weight
625.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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