Verubecestat tosylate
Product Specifications
CAS Number
1875153-95-9
Target
Others, Beta-Secretase
Related Pathways
Others, Neuroscience
Bioactivity
Verubecestat tosylate, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat tosylate is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat tosylate reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.
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Cc1ccc(cc1)S(O)(=O)=O.CN1C(N)=N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
Molecular Formula
C25H26N4O4S2
Molecular Weight
510.627
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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