Mps1-IN-1 dihydrochloride
Product Specifications
CAS Number
1883548-93-3
Target
Kinesin, Others
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM. It effectively inhibits the activity of Mps1 mitotic kinase and disrupts spindle assembly checkpoint (SAC) function, thereby reducing the viability of both cancerous and 'normal' cells.
Smiles
Cl.Cl.O=S(=O)(C=1C=CC=CC1NC=2C=C(N=C3NC=CC32)NC4=CC=C(C=C4OC)N5CCC(O)CC5)C(C)C
Molecular Formula
C28H35Cl2N5O4S
Molecular Weight
608.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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