JNJ-61803534
Product Specifications
CAS Number
1917306-14-9
Target
Others, ROR
Related Pathways
Metabolism, Others
Bioactivity
JNJ-61803534 is a potent, orally active RORγt inverse agonist, demonstrating anti-inflammatory activity through inhibition of IL-17A production in human CD4+ T cells under Th17 differentiation conditions, with an IC50 of 9.6 nM.
Smiles
C[C@@H]1CCCN1C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(=O)NCC(C)(C)O
Molecular Formula
C23H23Cl2F6N3O4S
Molecular Weight
622.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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