Apricoxib
Product Specifications
CAS Number
197904-84-0
Target
Others, Prostaglandin Receptor, COX
Related Pathways
Immunology/Inflammation, Others, GPCR/G Protein, Neuroscience
Bioactivity
Apricoxib, also known as Benzenesulfonamide 42 (4ethoxyphenyl) 4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.
Smiles
CC=1C=C(N(C1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC=C(OCC)C=C3
Molecular Formula
C19H20N2O3S
Molecular Weight
356.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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