GSK563
Product Specifications
CAS Number
1983928-04-6
Target
Others
Related Pathways
Others
Bioactivity
GSK563 is a potent GVIA iPLA2 inhibitor (XI (50) 0.0000021, IC50 1 nM) . GSK563 is 22 000 times more active against GVIA iPLA2 than GIVA cPLA2. It was found to reduce ?-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.
Smiles
C(CC)C1C(CCCCC2=CC=CC=C2)C(=O)O1
Molecular Formula
C16H22O2
Molecular Weight
246.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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