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Bomedemstat ditosylate

Product Specifications

CAS Number

1990504-72-7

Target

Apoptosis, Histone Demethylase

Related Pathways

Apoptosis, Chromatin/Epigenetic

Purity

0.9905

Bioactivity

Bomedemstat ditosylate (IMG-7289 ditosylate) is an orally active lysine-specific demethylase 1 (LSD1) inhibitor with antitumor activity that potentiates the response to PD-1 inhibition in a homozygous model of SCLC, inhibits cancer cell proliferation, and induces apoptosis. Bomedemstat ditosylate can be used to study myeloproliferative neoplasms and myelofibrosis.

Smiles

Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.[H][C@]1(C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1ccnn1)C(=O)N1CCN(C)CC1)c1ccc(F)cc1

Molecular Formula

C42H50FN7O8S2

Molecular Weight

864.02

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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