Ruboxistaurin mesylate monohydrate
Product Specifications
CAS Number
202260-21-7
Target
Others
Related Pathways
Others
Bioactivity
Ruboxistaurin mesylate monohydrate is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-?1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
Smiles
O.CS(O)(=O)=O.CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21
Molecular Formula
C29H34N4O7S
Molecular Weight
582.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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