Ixazomib citrate EtOH
Product Specifications
CAS Number
2026591-78-4
Target
Others
Related Pathways
Others
Bioactivity
Ixazomib citrate, also known as MLN9708, is a prodrug of Ixazomib (MMLN-2238) . MLN9708 is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. MLN9708, after hydrolyzing to pharmacologically active MLN2238 (ixazomib), is a next-generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity. MLN9708, compared with bortezomib, has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies.
Smiles
CCO.CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)C(CC(O)=O)(CC(O)=O)O1
Molecular Formula
C22H29BCl2N2O10
Molecular Weight
563.188
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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