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KR30031

Product Specifications

CAS Number

205535-74-6

Target

Others, P-gp

Related Pathways

Others, Membrane transporter/Ion channel, Neuroscience

Bioactivity

KR30031 is a novel P-glycoprotein inhibitor with potential anticancer activity. KR30031 is a verapamil analog with fewer cardiovascular effects. The ability of KR-30031 to reduce this efflux transport is equal to that of verapamil, a well-known P-glycoprotein inhibitor. The bioavailability of paclitaxel could be enhanced by coadministration of a P-glycoprotein inhibitor, KR-30031.

Smiles

C(CCN(CCC1=CC(OC)=C(OC)C=C1)C)C2(C#N)C=3C(CC2)=C(OC)C(OC)=CC3

Molecular Formula

C26H34N2O4

Molecular Weight

438.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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