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Delgocitinib EtOH

Product Specifications

CAS Number

2064338-33-4

Target

Others|||JAK

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Stem Cells|||Others|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Bioactivity

Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.

Smiles

CCO.C[C@H]1CN(C(=O)CC#N)[C@]11CCN(C1)c1ncnc2[nH]ccc12

Molecular Formula

C18H24N6O2

Molecular Weight

356.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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