Delgocitinib EtOH
Product Specifications
CAS Number
2064338-33-4
Target
Others|||JAK
Related Pathways
Angiogenesis|||JAK/STAT signaling|||Stem Cells|||Others|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Bioactivity
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.
Smiles
CCO.C[C@H]1CN(C(=O)CC#N)[C@]11CCN(C1)c1ncnc2[nH]ccc12
Molecular Formula
C18H24N6O2
Molecular Weight
356.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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