LEO 134310
Product Specifications
CAS Number
2089130-74-3
Target
Others, Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones, Others
Bioactivity
LEO 134310, a selective, non-steroidal glucocorticoid receptor (GR) agonist, is optimized for topical treatment. Demonstrating high affinity (EC50 of 14 nM) in GR binding assays, it is suitable for treating skin diseases.
Smiles
[C@H](OC1=CC=C(C(O[C@@H]2CN(C(=O)[C@@H]3CC(=O)OC3)CCC2)=O)C=C1)([C@@H](NC(=O)[C@H]4CCCO4)C)C5=CC=C(C=C5)C6CC6
Molecular Formula
C34H40N2O8
Molecular Weight
604.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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