NVR3-778 hydrate
Product Specifications
CAS Number
2093094-04-1
Target
Others
Related Pathways
Others
Bioactivity
NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV) -infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40 μM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos (t) ide inhibitors of HBV replication.
Smiles
O.OC1CCN(CC1)S(=O)(=O)c1cc(ccc1F)C(=O)Nc1cc(F)c(F)c(F)c1
Molecular Formula
C18H18F4N2O5S
Molecular Weight
450.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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